Nadya, a 3-year-old Amur tiger at the Minnesota Zoo, died unexpectedly over the weekend, zoo officials said.
The tiger had been ailing the week before her death, but veterinarians and zookeepers could not determine what caused her illness.
As her situation worsened, she underwent emergency exploratory surgery, which was inconclusive. She died after surgery.
The zoo is awaiting a necropsy, or animal autopsy, from the University of Minnesota, to solve the mystery of her death.
"We are very sad over the unexpected passing of Nadya," Kevin Willis, the Minnesota Zoo's vice president for biological programs, said in a news release. "Because she was hand-raised here, she was one of our favorite animals, and despite receiving the very best in medical care, she unfortunately didn't survive. She will always be remembered by staff and volunteers as a sweet-natured tiger."
When Nadya became lethargic and stopped eating, a blood test revealed compromised liver function, Willis said. She was given pain medication, but still would not eat. On Saturday, the zoo conducted a laparoscopy on Nadya and then surgery with the help of BluePearl's specialty and emergency veterinarians.
When the anesthetic was withdrawn, Nadya went into cardiac arrest. Officials resuscitated her and shifted her back into the holding building, where she went into cardiac arrest again.
Nayda had no preexisting conditions, Willis said. "This one stands out to me because she was so young," he said.