BALTIMORE — Anthony Santander hit a grand slam off Bryan Abreu in the eighth inning, carrying the Baltimore Orioles to a 7-5 comeback victory over the Houston Astros on Friday night.
Baltimore managed only three hits and trailed 5-2 before rallying to end Houston's nine-game road winning streak. Colton Cowser and Adley Rutschman singled before Abreu (2-2) snagged a comebacker but was late trying to get Cowser leaning off third base, loading the bases.
''The route you want him to go is a 1-6-3 double play,'' manager Joe Espada said. ''But his first reaction is, he sees the runner break and instincts take over.''
Santander then ripped a 2-1 fastball over the right-field wall for his 38th home run of the season. His second slam this season and the fourth of his career set off a wild celebration among the crowd of nearly 40,000.
''I'm so happy the fans stayed in that kind of game to support us,'' Santander said.
Ramón Urías tacked on an RBI triple to cap the five-run outburst.
Craig Kimbrel (7-4) worked the eighth and Seranthony Domínguez got three outs for his fifth save, the fourth since coming to Baltimore in a July trade with Philadelphia.
Jose Altuve and Jeremy Peña homered for Houston, and starter Hunter Brown pitched six innings of three-hit ball.