A boy with HIV and leukemia, who underwent an experimental cell transplant at University of Minnesota's Amplatz Children's Hospital, has died of complications from the procedure, his doctors said Friday.
Twelve-year-old Eric Blue, of Alexandria, La., had not been publicly identified until Friday, when university officials released a statement confirming that he died July 5, nearly three months after the risky — and potentially historic — procedure.
Blue was in line to become the second person in the world to be cured of both deadly illnesses by the extraordinary type of bone marrow transplant, doctors said.
"He was incredibly brave and courageous, and understood he was participating in something historic," said Dr. Michael Verneris, a transplant specialist at the university, who treated Blue.
In June, Blue developed a severe complication called graft-versus-host disease, which occurs when the immune cells of the donor attack various tissues of the body.
"Sometimes the disease is a very treatable problem," said Verneris. "Unfortunately in his circumstance, for whatever reason, it was worse than it would otherwise be … he had an especially bad form of it."
Until Friday, Blue's identity had been withheld for privacy reasons. But his mother granted permission to reveal his name following his death to acknowledge her son's pioneering medical contributions, according to U officials.
The procedure, which was performed April 23, involved injecting Blue with blood cells from a donor with a rare genetic resistance to HIV, the virus that causes AIDS. Less than 1 percent of the population is born with this genetic resistance, according to Verneris. Doctors hoped the transplant would rid the boy's body of both the leukemia and HIV and help fight off any recurrence.
