The Lynx waived veteran point guard Layshia Clarendon on Tuesday ahead of Friday's opener at Seattle.
Eight-year veteran guard Odyssey Sims also signed a training camp contract to cap a whirlwind day of roster moves.
Also cut were guards Crystal Dangerfield and Yvonne Turner, forwards Rennia Davis and Kayla Jones and center Hannah Sjerven.
The Lynx roster now has 11 players, and with Damiris Dantas injured, Kayla McBride overseas and Napheesa Collier expecting a child, the team applied to the WNBA for two hardship spots. Waived players must clear a 48-hour window before they can sign a new contract.
By making those cuts Tuesday, it's possible that one or both of those replacement contracts could go to players cut by the Lynx and still have them ready to play in the season opener.
A right fibula stress fracture hampered Clarendon at the end of last season and flared up again during the preseason.
"It wasn't that Lay became a bad basketball player," Lynx coach Cheryl Reeve said. "It had nothing to do with Lay's abilities to lead or play. Just, we didn't feel like, to start the season, we were in a good place physically."
Clarendon arrived in Minnesota after the Lynx got out to an 0-4 start last season, powering them to a 22-10 record and the No. 3 seed in the playoffs. Clarendon was also in the spotlight as the first openly nonbinary player in the league. They signed a one-year, non-guaranteed $90,000 contract with Minnesota in February, but the injury never fully healed, causing soreness that held them out of the first preseason game against Washington and to limited minutes on Sunday against Las Vegas. Had they made the final 11-player roster, their contract would have become fully guaranteed.