NEW YORK — Stocks that traded heavily or had substantial price changes on Friday:

Sarepta Therapeutics Inc., up $37.22 to $160.72.

U.S. regulators approved the company's treatment for children with Duchenne muscular dystrophy.

Trump Media & Technology Group Corp., up 91 cents to $27.66.

The owner of Donald Trump's Truth Social has lost half its value since the former president was convicted in a case involving hush money paid to a porn actor.

Ryan Specialty Holdings Inc., up $4.24 to $59.60.

The specialty insurance firm is being added to the S&P MidCap 400 index.

Asana Inc., up $1.74 to $13.11.

The work management software company announced a $150 million stock buyback program.

FactSet Research Systems Inc., up $15.38 to $423.73.

The financial data provider's earnings came in well ahead of analysts' forecasts.

Autodesk Inc., down $1.20 to $242.31.

A court denied an investor's motion to expedite a lawsuit that could have delayed the software company's shareholder meeting.

Hertz Global Holdings Inc., up 56 cents to $4.07.

The car rental company increased an upcoming bond offering to $1 billion.

CarMax Inc., up 27 cents to $71.63.

The used car chain delivered profit for the latest quarter that edged past analysts' expectations.