Pope Francis is in critical condition after long respiratory crisis, requiring oxygen at high flow

ROME — Pope Francis was in critical condition Saturday after he suffered a long asthmatic respiratory crisis that required high flows of oxygen, the Vatican said.

The 88-year-old Francis, who has been hospitalized for a week with pneumonia and a complex lung infection, also received blood transfusions after tests showed low platelet counts associated with anemia, the Vatican said in a late update.

‘‘The Holy Father continues to be alert and spent the day in an armchair although in more pain than yesterday. At the moment the prognosis is reserved,‘’ the statement said.

Doctors have said Francis' condition is touch-and-go and that he is by no means out of danger.

They have warned that the main threat facing Francis would be the onset of sepsis, a serious infection of the blood that can occur as a complication of pneumonia. As of Friday, there was no evidence of any sepsis, and Francis was responding to the various drugs he is taking, the pope’s medical team said in their first in-depth update on the pope’s condition.

Francis, who has chronic lung disease, was admitted to Gemelli hospital on Feb. 14 after a weeklong bout of bronchitis worsened.

Doctors first diagnosed the complex viral, bacterial and fungal respiratory tract infection and then the onset of pneumonia in both lungs. They prescribed ‘’absolute rest'' and a combination of cortisone and antibiotics, along with supplemental oxygen when he needs it.

Dr. Sergio Alfieri, the head of medicine and surgery at Rome’s Gemelli hospital, said the biggest threat facing Francis was that some of the germs that are currently located in his respiratory system pass into the bloodstream, causing sepsis. Sepsis can lead to organ failure and death.

‘‘Sepsis, with his respiratory problems and his age, would be really difficult to get out of,‘’ Alfieri told a news conference Friday at Gemelli. ‘’The English say ‘knock on wood,’ we say ‘touch iron.’ Everyone touch what they want,‘’ he said as he tapped the microphone. ‘’But this is the real risk in these cases: that these germs pass to the bloodstream.‘’

‘‘He knows he’s in danger,‘’ Alfieri added. ‘’And he told us to relay that.‘’

Meanwhile, the Vatican hierarchy went on the defensive to tamp down rumors and speculation that Francis might decide to resign. There is no provision in canon law for what to do if a pope becomes incapacitated. Francis has said that he has written a letter of resignation that would be invoked if he were medically incapable of making such a decision. The pope remains fully conscious, alert, eating and working.

The Vatican secretary of state, Cardinal Pietro Parolin, gave a rare interview to Corriere della Sera to respond to speculation and rumors about a possible resignation. It came after the Vatican issued an unusual and official denial of an Italian media report that said Parolin and the pope’s chief canonist had visited Francis in the hospital in secret. Given the canonical requirements to make a resignation legitimate, the implications of such a meeting were significant, but the Vatican flat-out denied that any such meeting occurred.

Parolin said such speculation seemed ‘’useless'' when what really mattered was the health of Francis, his recovery and return to the Vatican.

‘‘On the other hand, I think it is quite normal that in these situations uncontrolled rumors can spread or some misplaced comment is uttered. It is certainly not the first time it has happened,‘’ Parolin was quoted as saying. ‘’However, I don’t think there is any particular movement, and so far I haven’t heard anything like that.‘’

Deacons, meanwhile, were gathering at the Vatican for their special Holy Year weekend. Francis got sick at the start of the Vatican’s Holy Year, the once-every-quarter-century celebration of Catholicism. This weekend, Francis was supposed to have celebrated deacons, a ministry in the church that precedes ordination to the priesthood.

In his place, the Holy Year organizer will celebrate Sunday’s Mass, the Vatican said. And for the second consecutive weekend, Francis was expected to skip his traditional Sunday noon blessing, which he could have delivered from Gemelli if he were up to it.

‘‘Look, even though he’s not (physically) here, we know he’s here,‘’ said Luis Arnaldo López Quirindongo, a deacon from Ponce, Puerto Rico, who was at the Vatican on Saturday for the Jubilee celebration. ‘’He’s recovering, but he’s in our hearts and is accompanying us, because our prayers and his go together.‘’

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