For decades, becoming a pharmacist and running your own drugstore yielded a good living and a rewarding sense of service to others.
Over the last decade, however, Minnesota has lost more independent pharmacies than any other state.
This problem is emblematic of an industry that has tilted too far in the direction of scale and efficiency as drugstore chains gobble up market share. It's been exacerbated by the rise of middlemen known as pharmacy benefit managers, or PBMs.
A century ago, drugstores sprouted up in every town of more than a thousand people and in most neighborhoods of Minneapolis and St. Paul.
Operating an independent pharmacy has become more financially difficult, said Deborah Keaveny, who co-owns Keaveny Drug in Winsted, about an hour west of the Twin Cities.
"Pharmacy used to be a noble business. We were never rich, but we were OK," Keaveny said. "Now, a lot of us have mortgaged our houses. We've cut our own wages. We have reduced staff as much as we possibly can. If you've got an independent pharmacy that's still around, man, they have been through the wringer."
Drug delivery has become enormously complex, with numerous intermediaries and convoluted pricing models. On Tuesday, CVS Health, the nation's No. 2 drugstore chain, said it would abandon complex price schemes for a simple mark-up on wholesale costs.
Independent pharmacies provide a measure of resilience and flexibility in the industry. They're often the only option in small communities.